Endocrine Abstracts

Introduction: Research in the past two decades has shown that Fenugrec seeds help to lower blood glucose in patients with diabetes. Its role as an antidiabetic, by reducing fasting blood glucose levels and improved glucose tolerance in human subjects was reported Curcuminoids have been shown to improve insulin resistance, decrease glucose and insulin levels, increase adiponectin release, and reduce the levels of leptin, resistin, interleukin (IL)-6 IL-1b, and tumor necrosis fa...

Introduction: Type 2 diabetes is an important risk factor for all forms of infection. It may be unrecognised for many years, and often revealed by degenerative or infectious complications. The aim of this study is to investigate the epidemiological, clinical and therapeutic aspects of severe infections revealing type 2 diabetes.Patients and Methods: Retrospective descriptive cross-sectional study of a series of 5 patients with severe infections revealing...

Introduction: The COVID pandemic was a challenge in terms of physiopathology and therapeutics. Diabetics represent more than 40% of patients hospitalized for COVID. There was many new cases of diabetes declared during or after a COVID. The purpose of this report is to raise the link between Sars-Cov-2 infection and the appearance of glycemic disorders and new cases of diabetes.Case Presentation 1: A 28-years-old man who had a serious COVID-19 a month ago...

Introduction: Benzold abscess remains rare, and its occurrence implies immunosuppression, particularly within unbalanced diabetes.Methods and Results: Observation of a 76-year-old patient, diabetic for 29 years, on metformin, admitted for CMO of the right ear, complicated by Bezold’s abscess. The interrogation revealed purulent otorrhea hypoacusis. The clinical examination revealed hyperglycemia, a swelling of the sternocleidomastoid, responsible fo...

Introduction: Digital necrosis of the upper limbs is the final and often the only clinical manifestation of a of a distal arterial or microcirculatory pathology of the MS. The approach to The approach to this condition is very different, hence the particularity of our observation which highlights the severity of vascular lesions found in diabetic patients.Observation: This is a 58 year old diabetic patient on mixtard 30: 16-00-08 ui; schizophrenia; on cl...

Introduction: Diabetic osteoarthropathy (D.O) commonly referred to as Charcot’s foot is a complication secondary to neuropathic and inflammatory osteolysis, occurring in a setting of old and/or poorly controlled diabetes. Its pathophysiology remains poorly understood and its diagnosis must be systematically evoked in the presence of any inflammatory sign that localised to the foot or ankle occurring on a background of diabetic neuropathy.Clinical ca...

Introduction: Human immunodeficiency virus (HIV) infection and certain antiretroviral (ARV) treatments are associated with an increased risk of developing certain chronic comorbidities including type 2 diabetes, which is more prevalent in HIV-infected individuals. The coexistence of diabetes and HIV infection makes the standard of care more complex. The objective of this work is to discuss the relationship between these two comorbidities and to update physicians on the diagnos...

Introduction: Sinonasal neuroendocrine carcinoma SNECs are a rare group of neoplasms that account for only 5% of all sinonasal malignancies. SNECs are categorized by their differentiation grade into well-, moderately- and poorly differentiated.Case report: We describe a classical case of SNEC with secondary orbital involvement in a 34-year-old male patient presented of the occurrence of a right epistaxis. First of all, the patient is smoking. The beginni...

Introduction: Malignant tumors, nevertheless, have been associated with extremely high circulating ACTH and cortisol levels, and short duration of symptoms of Cushing syndrome (CS) besides atypical clinical phenotype, when compared with pituitary-dependent Cushing. Identification of the source of ACTH can be challenging, as sometimes the primary lesion is not identified even after prolonged and repeated follow-upCase report: A 33-year-old woman with a hi...

Introduction: Familial neurohypophysial diabetes insipidus (FNDI), an autosomal dominant disorder, comes in many forms that are differentiated by the inheritance pattern and the underlying genetic lesion. The disease is caused by mutations in the vasopressin-neurophysin 2-copeptin protein (AVP-NPII), in wolframin (WFS1) or in proprotein convertase subtilisin/kexin type 1 (PCSK1) genes.Materials and methods: In this study, we report a case of familial neu...